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To determine the best reagent for a specific assay, check the experimental protocol or published literature to see what has been validated for that reaction. Consider purity, concentration, stability, and compatibility with your other reagents. For storage and handling, follow the manufacturer’s instructions. Many reagents need refrigeration, protection from light, and avoidance of moisture. Minimize freeze-thaw cycles and always use clean, dry tools to prevent contamination. When working with any laboratory research reagent, it’s important to read the datasheet carefully and understand its properties. When interpreting datasheets, prioritize purity, concentration, stability, storage conditions, and safety hazards. Trusted suppliers include Sigma-Aldrich, Thermo Fisher, and Merck. Label reagents with the date opened and track usage for best practices.